Over many decades now, traditional drug discovery methods have steadily improved at keeping diseases at bay and cancer in remission. And for the most part, it’s worked well.
Researchers at the University of Pittsburgh School of Medicine have discovered a blood biomarker that predicts kidney transplant rejection with a lead time of about eight months, which could give doctors an opportunity to intervene and prevent permanent damage.
Immunologists at St. Jude Children’s Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system.
Rheumatoid arthritis is a chronic inflammatory disorder marked by joint pain, swelling and damage. Although medications, such as steroids, anti-inflammatory drugs and immunosuppressants, can help slow joint destruction and relieve pain, they have side effects and aren’t completely successful.
Neuroblastoma is a cancer that develops in nerve tissue, most commonly in the glands around the kidneys. The gene MYCN is overexpressed in 20-25% of neuroblastoma, and MYCN-amplified neuroblastoma contributes to a considerable percentage of pediatric cancer-related deaths.
A new study in the Journal of dietary supplements shows that nutritional supplements, including several vitamins and the mineral zinc, may be useful in preventing the infection or reducing its severity if caught.
Muscle soreness and achy joints are common symptoms among COVID-19 patients. But for some people, symptoms are more severe, long-lasting, and even bizarre, including rheumatoid arthritis flares, autoimmune myositis, or “COVID toes.”
Researchers at the University of Tsukuba in Japan show that simulating an overactive autoimmune response in mice leads to changes in the hippocampal region of the brain.
People who have a gene variant associated with an increased risk of developing Alzheimer’s disease also tend to have changes in the fluid around their brain and spinal cord that are detectable years before symptoms arise, according to new research from Duke Health.
A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility.